Search results for "Cardiac performance"

showing 3 items of 3 documents

Bigger is not better: cortisol-induced cardiac growth and dysfunction in salmonids

2015

This is a Published Manuscript of an article published by Company of Biologists in Journal of Experimental Biology, available online: http://www.biologists.com/ Stress and elevated cortisol levels are associated with pathological heart growth and cardiovascular disease in humans and other mammals. We recently established a link between heritable variation in post-stress cortisol production and cardiac growth also in salmonid fish. A conserved stimulatory effect of the otherwise catabolic steroid hormone cortisol is likely implied, but has to date not been established experimentally. Furthermore, whereas cardiac growth is associated with failure of the mammalian heart, pathological cardiac h…

Male0301 basic medicinemedicine.medical_specialtyendocrine systemHydrocortisonePhysiologyGene ExpressionHeart failureCardiac performance030204 cardiovascular system & hematologyAquatic ScienceBiologyBioinformatics03 medical and health sciences0302 clinical medicineSDG 3 - Good Health and Well-beingInternal medicinemedicineAnimalsChronic stressCardiac OutputMolecular BiologySwimmingEcology Evolution Behavior and SystematicsVentricular RemodelingHeartStroke VolumeHypertrophyMyocardial hypertrophymedicine.diseasePeer reviewRainbow trout030104 developmental biologyEndocrinologyOncorhynchus mykissInsect ScienceHeart failureMyocardial hypertrophy/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingExperimental biologyChronic stressFemaleAnimal Science and ZoologyRainbow trout
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Receptor identification and physiological characterisation of glucagon-like peptide-2 in the rat heart.

2010

Abstract Background and aims The anorexigenic glucagon-like peptide (GLP)-2 is produced by intestinal L cells and released in response to food intake. It affects intestinal function involving G-protein-coupled receptors. To verify whether GLP-2 acts as a cardiac modulator in mammals, we analysed, in the rat heart, the expression of GLP-2 receptors and the myocardial and coronary responses to GLP-2. Methods and results GLP-2 receptors were detected on ventricular extracts by quantitative real-time polymerase chain reaction (Q-RT-PCR) and Western blotting. Cardiac GLP-2 effects were analysed on Langendorff perfused hearts. Intracellular GLP-2 signalling was investigated on Langendorff perfuse…

Maleendocrine systemmedicine.medical_specialtyCardiotonic AgentsNitric Oxide Synthase Type IIIMAP Kinase Signaling SystemG proteinEndocrinology Diabetes and MetabolismBlotting WesternMedicine (miscellaneous)Enzyme-Linked Immunosorbent AssayStimulationIn Vitro TechniquesBiologyReal-Time Polymerase Chain Reactionglucagon-like peptides-2 gut peptides cardiac performanceSettore BIO/09 - FisiologiaGlucagon-Like Peptide-1 Receptorchemistry.chemical_compoundInternal medicineCyclic AMPCyclic GMP-Dependent Protein KinasesGlucagon-Like Peptide 2Receptors GlucagonmedicineAnimalsCyclic adenosine monophosphatePhosphorylationRats WistarReceptorNutrition and Dieteticsdigestive oral and skin physiologyHeartPeptide FragmentsRatsPhospholambanEndocrinologyGene Expression RegulationchemistryInotropismGlucagon-Like Peptide-2 ReceptorCardiology and Cardiovascular MedicinecGMP-dependent protein kinasehormones hormone substitutes and hormone antagonistsIntestinal L CellsSignal Transduction
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The emerging myocardial and coronary action of Glucagon-derived peptide-2.

2010

Settore BIO/09 - Fisiologiagut peptides cardiac performance
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